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Biology Ribble Endowment Seminar

"The Molecular Circadian Clock and the Impact of Disrupted Rhythms and Sleep on Health and Disease"

Turek Selfie

Dr. Fred Turek

Bio:
Fred W. Turek, PhD received his undergraduate degree in the biological sciences from Michigan State University in 1969, and his PhD from Stanford University in 1973 where he carried out research on circadian and seasonal rhythms.  After postdoctoral training at the University of Texas at Austin, he took a faculty position at Northwestern University where he served as the Chair of the Department of Neurobiology & Physiology from 1987-98.  Dr. Turek is the founder and current Director of the Center for Sleep and Circadian Biology at Northwestern University.  Dr. Turek was the founding president of the Society for Research on Biological Rhythms (SRBR) and served in this capacity for six years.

Watch the seminar here!

 

 

Date:
Location:
THM 116

"Genetic, Social, and Developmental Drivers of Within-population Behavioral Variation"

Laskowski Selfie

Dr. Kate Laskowski | Laskowski Lab

Bio:
Dr. Kate Laskowski is interested in investigating how evolution has shaped the developmental processes that generate behavioral individuality. She does this by generating replicate individuals and groups of the naturally clonal fish, the Amazon molly, allowing her to “replay the developmental clock.” Kate obtained her Bachelor’s of Science at the University of Maryland Baltimore County and her PhD from the University of Illinois where she worked under Alison Bell. She then moved to Berlin Germany to work at the Leibniz Institute of Freshwater Ecology & Inland Fisheries with Max Wolf and Jens Krause before joining the Department of Evolution & Ecology at the University of California Davis in 2019.  

Abstract:
Individual behavioral variation is ubiquitous across the animal kingdom. Explaining the continued generation and maintenance of such variation is a fundamental goal in behavioral and evolutionary ecology. Our research tests key predictions drawn from theoretical models about how genetic correlations and developmental processes can drive the emergence of consistent individual behavioral variation. This work has shown that competition for, and acquisition of, resources may play key roles in shaping behavior variation both on evolutionary and developmental timescales. Using the clonal Amazon molly and an innovative high-resolution tracking system we can follow and manipulate individual experience with salient environmental cues such as resource availability and relative risk. We can track the behavioral development of individual fish from birth in, up to now, unprecedented detail, allowing us to pinpoint exactly when and in response to which cues individuality emerges. Our results highlight that in order to fully explain the presence of individual behavioral variation we need a comprehensive conceptual framework that explicitly accounts for how natural selection has shaped the developmental process.
 

Watch the seminar here!

Laskowski Fish

Date:
Location:
THM 116

"Genetic, Social, and Developmental Drivers of Within-population Behavioral Variation"

Laskowski Selfie

Dr. Kate Laskowski | Laskowski Lab

Bio:
Dr. Kate Laskowski is interested in investigating how evolution has shaped the developmental processes that generate behavioral individuality. She does this by generating replicate individuals and groups of the naturally clonal fish, the Amazon molly, allowing her to “replay the developmental clock.” Kate obtained her Bachelor’s of Science at the University of Maryland Baltimore County and her PhD from the University of Illinois where she worked under Alison Bell. She then moved to Berlin Germany to work at the Leibniz Institute of Freshwater Ecology & Inland Fisheries with Max Wolf and Jens Krause before joining the Department of Evolution & Ecology at the University of California Davis in 2019.  

Abstract:
Individual behavioral variation is ubiquitous across the animal kingdom. Explaining the continued generation and maintenance of such variation is a fundamental goal in behavioral and evolutionary ecology. Our research tests key predictions drawn from theoretical models about how genetic correlations and developmental processes can drive the emergence of consistent individual behavioral variation. This work has shown that competition for, and acquisition of, resources may play key roles in shaping behavior variation both on evolutionary and developmental timescales. Using the clonal Amazon molly and an innovative high-resolution tracking system we can follow and manipulate individual experience with salient environmental cues such as resource availability and relative risk. We can track the behavioral development of individual fish from birth in, up to now, unprecedented detail, allowing us to pinpoint exactly when and in response to which cues individuality emerges. Our results highlight that in order to fully explain the presence of individual behavioral variation we need a comprehensive conceptual framework that explicitly accounts for how natural selection has shaped the developmental process.
 

Watch the seminar here!

Laskowski Fish

Date:
Location:
THM 116

"Genetic, Social, and Developmental Drivers of Within-population Behavioral Variation"

Laskowski Selfie

Dr. Kate Laskowski | Laskowski Lab

Bio:
Dr. Kate Laskowski is interested in investigating how evolution has shaped the developmental processes that generate behavioral individuality. She does this by generating replicate individuals and groups of the naturally clonal fish, the Amazon molly, allowing her to “replay the developmental clock.” Kate obtained her Bachelor’s of Science at the University of Maryland Baltimore County and her PhD from the University of Illinois where she worked under Alison Bell. She then moved to Berlin Germany to work at the Leibniz Institute of Freshwater Ecology & Inland Fisheries with Max Wolf and Jens Krause before joining the Department of Evolution & Ecology at the University of California Davis in 2019.  

Abstract:
Individual behavioral variation is ubiquitous across the animal kingdom. Explaining the continued generation and maintenance of such variation is a fundamental goal in behavioral and evolutionary ecology. Our research tests key predictions drawn from theoretical models about how genetic correlations and developmental processes can drive the emergence of consistent individual behavioral variation. This work has shown that competition for, and acquisition of, resources may play key roles in shaping behavior variation both on evolutionary and developmental timescales. Using the clonal Amazon molly and an innovative high-resolution tracking system we can follow and manipulate individual experience with salient environmental cues such as resource availability and relative risk. We can track the behavioral development of individual fish from birth in, up to now, unprecedented detail, allowing us to pinpoint exactly when and in response to which cues individuality emerges. Our results highlight that in order to fully explain the presence of individual behavioral variation we need a comprehensive conceptual framework that explicitly accounts for how natural selection has shaped the developmental process.
 

Watch the seminar here!

Laskowski Fish

Date:
Location:
THM 116

"Genetic, Social, and Developmental Drivers of Within-population Behavioral Variation"

Laskowski Selfie

Dr. Kate Laskowski | Laskowski Lab

Bio:
Dr. Kate Laskowski is interested in investigating how evolution has shaped the developmental processes that generate behavioral individuality. She does this by generating replicate individuals and groups of the naturally clonal fish, the Amazon molly, allowing her to “replay the developmental clock.” Kate obtained her Bachelor’s of Science at the University of Maryland Baltimore County and her PhD from the University of Illinois where she worked under Alison Bell. She then moved to Berlin Germany to work at the Leibniz Institute of Freshwater Ecology & Inland Fisheries with Max Wolf and Jens Krause before joining the Department of Evolution & Ecology at the University of California Davis in 2019.  

Abstract:
Individual behavioral variation is ubiquitous across the animal kingdom. Explaining the continued generation and maintenance of such variation is a fundamental goal in behavioral and evolutionary ecology. Our research tests key predictions drawn from theoretical models about how genetic correlations and developmental processes can drive the emergence of consistent individual behavioral variation. This work has shown that competition for, and acquisition of, resources may play key roles in shaping behavior variation both on evolutionary and developmental timescales. Using the clonal Amazon molly and an innovative high-resolution tracking system we can follow and manipulate individual experience with salient environmental cues such as resource availability and relative risk. We can track the behavioral development of individual fish from birth in, up to now, unprecedented detail, allowing us to pinpoint exactly when and in response to which cues individuality emerges. Our results highlight that in order to fully explain the presence of individual behavioral variation we need a comprehensive conceptual framework that explicitly accounts for how natural selection has shaped the developmental process.
 

Watch the seminar here!

Laskowski Fish

Date:
Location:
THM 116

"Genetic, Social, and Developmental Drivers of Within-population Behavioral Variation"

Laskowski Selfie

Dr. Kate Laskowski | Laskowski Lab

Bio:
Dr. Kate Laskowski is interested in investigating how evolution has shaped the developmental processes that generate behavioral individuality. She does this by generating replicate individuals and groups of the naturally clonal fish, the Amazon molly, allowing her to “replay the developmental clock.” Kate obtained her Bachelor’s of Science at the University of Maryland Baltimore County and her PhD from the University of Illinois where she worked under Alison Bell. She then moved to Berlin Germany to work at the Leibniz Institute of Freshwater Ecology & Inland Fisheries with Max Wolf and Jens Krause before joining the Department of Evolution & Ecology at the University of California Davis in 2019.  

Abstract:
Individual behavioral variation is ubiquitous across the animal kingdom. Explaining the continued generation and maintenance of such variation is a fundamental goal in behavioral and evolutionary ecology. Our research tests key predictions drawn from theoretical models about how genetic correlations and developmental processes can drive the emergence of consistent individual behavioral variation. This work has shown that competition for, and acquisition of, resources may play key roles in shaping behavior variation both on evolutionary and developmental timescales. Using the clonal Amazon molly and an innovative high-resolution tracking system we can follow and manipulate individual experience with salient environmental cues such as resource availability and relative risk. We can track the behavioral development of individual fish from birth in, up to now, unprecedented detail, allowing us to pinpoint exactly when and in response to which cues individuality emerges. Our results highlight that in order to fully explain the presence of individual behavioral variation we need a comprehensive conceptual framework that explicitly accounts for how natural selection has shaped the developmental process.
 

Watch the seminar here!

Laskowski Fish

Date:
Location:
THM 116

"Be Fruitful and Multiply: How Reproductive Capacity Evolves"

Selfie

Dr. Cassandra Extavour | Extavour Lab

Bio
Cassandra Extavour is a native of Toronto, where she attended the University of Toronto Schools and went on to obtain an Honors BSc at the University of Toronto with a specialist in Molecular Genetics and Molecular Biology, a Major in Mathematics and a Minor in Spanish. She obtained her PhD with Antonio Garcia Bellido at the Severo Ochoa Center for Molecular Biology at the Autonomous University of Madrid. She performed postdoctoral work first with Michalis Averof at the Institute for Molecular Biology and Biotechnology in Crete, Greece, and subsequently with Michael Akam at the University of Cambridge. At Cambridge she received a BBSRC Research Grant and became a Research Associate in the Department of Zoology. In 2007 she established her independent laboratory as an Assistant Professor in the Department of Organismic and Evolutionary Biology at Harvard University, where she was promoted to Associate Professor in 2011 and to Full Professor in 2014. In 2021 she became a Howard Hughes Medical Institute Investigator, and was named the Timken Professor of Organismic and Evolutionary Biology and of Molecular and Cellular Biology at Harvard. Click here to read more.

Abstract:
Reproduction is a crucial fitness parameter, essential for species survival and evolution. Despite its importance, there is massive variation in reproductive capacity across animals, even between very closely related species. Moreover, reproductive capacity can be modified by environmental and ecological factors. Our aim is to understand how genetic variation interacts with ecological variation to regulate distinct and reproductive capacities between species, to determine whether and how ecological variation contributes to the evolution of adaptive variation in reproductive capacity. Our approach takes advantage of the fact that in sexually reproducing animals, the number of offspring that an individual can produce is often predicted by the anatomy of the ovary or testis, the sites of gamete production. In female insects, ovaries are subdivided into egg-producing units called ovarioles, which are generated in species-specific numbers during development. Ovariole number, and correspondingly reproductive capacity, can vary by more than four orders of magnitude across insects. I will discuss our findings on the mechanisms of genetic and environmental control of ovariole number in closely and distantly related insect species, and their implications for the broader questions of the genetic and developmental basis of fitness-relevant evolutionary change.

Date:
Location:
THM 116

"Be Fruitful and Multiply: How Reproductive Capacity Evolves"

Selfie

Dr. Cassandra Extavour | Extavour Lab

Bio
Cassandra Extavour is a native of Toronto, where she attended the University of Toronto Schools and went on to obtain an Honors BSc at the University of Toronto with a specialist in Molecular Genetics and Molecular Biology, a Major in Mathematics and a Minor in Spanish. She obtained her PhD with Antonio Garcia Bellido at the Severo Ochoa Center for Molecular Biology at the Autonomous University of Madrid. She performed postdoctoral work first with Michalis Averof at the Institute for Molecular Biology and Biotechnology in Crete, Greece, and subsequently with Michael Akam at the University of Cambridge. At Cambridge she received a BBSRC Research Grant and became a Research Associate in the Department of Zoology. In 2007 she established her independent laboratory as an Assistant Professor in the Department of Organismic and Evolutionary Biology at Harvard University, where she was promoted to Associate Professor in 2011 and to Full Professor in 2014. In 2021 she became a Howard Hughes Medical Institute Investigator, and was named the Timken Professor of Organismic and Evolutionary Biology and of Molecular and Cellular Biology at Harvard. Click here to read more.

Abstract:
Reproduction is a crucial fitness parameter, essential for species survival and evolution. Despite its importance, there is massive variation in reproductive capacity across animals, even between very closely related species. Moreover, reproductive capacity can be modified by environmental and ecological factors. Our aim is to understand how genetic variation interacts with ecological variation to regulate distinct and reproductive capacities between species, to determine whether and how ecological variation contributes to the evolution of adaptive variation in reproductive capacity. Our approach takes advantage of the fact that in sexually reproducing animals, the number of offspring that an individual can produce is often predicted by the anatomy of the ovary or testis, the sites of gamete production. In female insects, ovaries are subdivided into egg-producing units called ovarioles, which are generated in species-specific numbers during development. Ovariole number, and correspondingly reproductive capacity, can vary by more than four orders of magnitude across insects. I will discuss our findings on the mechanisms of genetic and environmental control of ovariole number in closely and distantly related insect species, and their implications for the broader questions of the genetic and developmental basis of fitness-relevant evolutionary change.

Date:
Location:
THM 116

"Be Fruitful and Multiply: How Reproductive Capacity Evolves"

Selfie

Dr. Cassandra Extavour | Extavour Lab

Bio
Cassandra Extavour is a native of Toronto, where she attended the University of Toronto Schools and went on to obtain an Honors BSc at the University of Toronto with a specialist in Molecular Genetics and Molecular Biology, a Major in Mathematics and a Minor in Spanish. She obtained her PhD with Antonio Garcia Bellido at the Severo Ochoa Center for Molecular Biology at the Autonomous University of Madrid. She performed postdoctoral work first with Michalis Averof at the Institute for Molecular Biology and Biotechnology in Crete, Greece, and subsequently with Michael Akam at the University of Cambridge. At Cambridge she received a BBSRC Research Grant and became a Research Associate in the Department of Zoology. In 2007 she established her independent laboratory as an Assistant Professor in the Department of Organismic and Evolutionary Biology at Harvard University, where she was promoted to Associate Professor in 2011 and to Full Professor in 2014. In 2021 she became a Howard Hughes Medical Institute Investigator, and was named the Timken Professor of Organismic and Evolutionary Biology and of Molecular and Cellular Biology at Harvard. Click here to read more.

Abstract:
Reproduction is a crucial fitness parameter, essential for species survival and evolution. Despite its importance, there is massive variation in reproductive capacity across animals, even between very closely related species. Moreover, reproductive capacity can be modified by environmental and ecological factors. Our aim is to understand how genetic variation interacts with ecological variation to regulate distinct and reproductive capacities between species, to determine whether and how ecological variation contributes to the evolution of adaptive variation in reproductive capacity. Our approach takes advantage of the fact that in sexually reproducing animals, the number of offspring that an individual can produce is often predicted by the anatomy of the ovary or testis, the sites of gamete production. In female insects, ovaries are subdivided into egg-producing units called ovarioles, which are generated in species-specific numbers during development. Ovariole number, and correspondingly reproductive capacity, can vary by more than four orders of magnitude across insects. I will discuss our findings on the mechanisms of genetic and environmental control of ovariole number in closely and distantly related insect species, and their implications for the broader questions of the genetic and developmental basis of fitness-relevant evolutionary change.

Date:
Location:
THM 116

"Be Fruitful and Multiply: How Reproductive Capacity Evolves"

Selfie

Dr. Cassandra Extavour | Extavour Lab

Bio
Cassandra Extavour is a native of Toronto, where she attended the University of Toronto Schools and went on to obtain an Honors BSc at the University of Toronto with a specialist in Molecular Genetics and Molecular Biology, a Major in Mathematics and a Minor in Spanish. She obtained her PhD with Antonio Garcia Bellido at the Severo Ochoa Center for Molecular Biology at the Autonomous University of Madrid. She performed postdoctoral work first with Michalis Averof at the Institute for Molecular Biology and Biotechnology in Crete, Greece, and subsequently with Michael Akam at the University of Cambridge. At Cambridge she received a BBSRC Research Grant and became a Research Associate in the Department of Zoology. In 2007 she established her independent laboratory as an Assistant Professor in the Department of Organismic and Evolutionary Biology at Harvard University, where she was promoted to Associate Professor in 2011 and to Full Professor in 2014. In 2021 she became a Howard Hughes Medical Institute Investigator, and was named the Timken Professor of Organismic and Evolutionary Biology and of Molecular and Cellular Biology at Harvard. Click here to read more.

Abstract:
Reproduction is a crucial fitness parameter, essential for species survival and evolution. Despite its importance, there is massive variation in reproductive capacity across animals, even between very closely related species. Moreover, reproductive capacity can be modified by environmental and ecological factors. Our aim is to understand how genetic variation interacts with ecological variation to regulate distinct and reproductive capacities between species, to determine whether and how ecological variation contributes to the evolution of adaptive variation in reproductive capacity. Our approach takes advantage of the fact that in sexually reproducing animals, the number of offspring that an individual can produce is often predicted by the anatomy of the ovary or testis, the sites of gamete production. In female insects, ovaries are subdivided into egg-producing units called ovarioles, which are generated in species-specific numbers during development. Ovariole number, and correspondingly reproductive capacity, can vary by more than four orders of magnitude across insects. I will discuss our findings on the mechanisms of genetic and environmental control of ovariole number in closely and distantly related insect species, and their implications for the broader questions of the genetic and developmental basis of fitness-relevant evolutionary change.

Date:
Location:
THM 116